Category: DNA

A Broad Safety Assessment of the 9-Valent Human Papillomavirus Vaccine

A Broad Safety Assessment of the 9-Valent Human Papillomavirus Vaccine

Posted on by Brian Taylor

Surveys of mother and father point out security is their high concern about human papillomavirus (HPV) vaccination. A data-mining methodology not requiring pre-specification of well being final result(s) of curiosity or post-exposure interval(s) of probably elevated danger can examine for associations between an publicity and any of 1000’s of medically attended well being outcomes. The methodology was utilized to the 9-valent HPV vaccine (HPV9) to detect potential security issues. Data on 9-26-year-olds who had obtained HPV9 vaccine between November 4, 2016 and August 5, 2018, inclusive, have been extracted from Marketscan and analyzed for statistically important clustering of incident diagnoses inside the hierarchy of ICD-10-CM coded diagnoses and temporally inside the 1 yr after vaccination, utilizing the self-controlled tree-temporal scan statistic and TreeScan software program.

Only 56 days of post-vaccination enrollment was required; subsequent follow-up was censored at disenrollment. Multiple testing was adjusted for. The evaluation included 493,089 doses of HPV9. Almost all alerts resulted from temporal confounding, not sudden with a 1-year follow-up interval. The solely believable alerts have been for non-specific adversarial occasions (e.g., injection-site reactions and headache) on Days 1-2 after vaccination, with attributable dangers as little as 1 per 100,000 vaccinees. Considering the broad scope of the analysis and the excessive statistical energy, the findings of no particular critical adversarial occasions ought to present reassurance about this vaccine’s security.

Patients present process (chemo) radiotherapy for oropharyngeal squamous cell carcinoma (OPSCC) are at excessive danger of malnutrition throughout and after therapy. Malnutrition can result in poor tolerance to therapy, therapy interruptions, poor high quality of life (QOL) and probably diminished survival fee. Human papillomavirus (HPV) is now generally known as the main trigger of OPSCC. However, analysis relating to its impact on dietary outcomes is proscribed. The purpose of this research was to look at the relationship between HPV standing and dietary outcomes, together with malnutrition and weight reduction throughout and after sufferers’ (chemo) radiotherapy therapy for OPSCC.

Epidemiology and Burden of Human Papillomavirus and Related Diseases, Molecular Pathogenesis, and Vaccine Evaluation

Diagnosed in additional than 90% of cervical cancers, the fourth deadliest most cancers in ladies, human papillomavirus (HPV) is at the moment the commonest pathogen accountable for feminine cancers. Moreover, HPV an infection is related to many different ailments, together with cutaneous and anogenital warts, and genital and higher aerodigestive tract cancers. The incidence and prevalence of these pathologies fluctuate significantly relying on components together with HPV genotype, regional situations, the research inhabitants, and the anatomical web site sampled. Recently, options of the cervicovaginal microbiota are discovered to be related to the incidence of HPV-related ailments, presenting a novel method to establish high-risk ladies by way of each blood and cervical samples.

Overall, the HPV repartition information present that HPV an infection and associated ailments are extra prevalent in creating nations. Moreover, the out there (2-, 4-, and 9-valent) vaccines based mostly on virus-like particles, regardless of their confirmed effectiveness and security, current some limitations in phrases of system improvement price, transport chilly chain, and oncogenic HPV variants. In addition, vaccination applications face some challenges, resulting in a substantial burden of HPV an infection and associated ailments. Therefore, although the new (9-valent) vaccine appears promising, next-generation vaccines in addition to consciousness applications related to HPV vaccination and price range reinforcements for immunization are wanted.

Clinical traits and tumors of 119 NSND with HNSCC have been retrospectively collected and analyzed on tissue microarrays. RNAscope in situ hybridization (ISH) was used to display for the presence of HPV and MCPyV mRNA. Immunohistochemistry was carried out for expression of p16 as surrogate marker for HPV, Large T-antigen for MCPyV, and cell cycle proteins p53 and pRb. Positive virus outcomes have been confirmed with polymerase chain response. For EBV, EBV encoded RNA ISH was carried out. Differences in 5-year survival between virus constructive and detrimental tumors have been decided by log rank evaluation.

A Broad Safety Assessment of the 9-Valent Human Papillomavirus Vaccine

Split-type electrochemiluminescent gene assay platform based mostly on gold nanocluster probe for human papillomavirus prognosis

Persistent high-risk human papillomavirus (HPV) an infection is the main trigger of cervical most cancers. Efficient detection of HPV16 E7 is critical for early prognosis and remedy of the illness. Here, a novel and high-performance Au nanocluster (AuNC) probe-based split-type electrochemiluminescent (ECL) assay platform has been established to detect these oncogenes, during which the nucleic acid hybridization assay and the ECL measurements are carried out independently. The proposed method combines superior magnetic nanobead enrichment and separation know-how, particular nucleic acid hybridization know-how, and high-efficiency AuNC probe ECL technique, and reveals wonderful benefits.

Anti-Papillomavirus type 1E2-protein Antibody
STJ60004 100 µg
EUR 424
Description: N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth

Anti-Papillomavirus type 1E2-protein Antibody
STJ60005 100 µg
EUR 424
Description: N-acetyl-D-glucosamine / N-acetyl-D-neuraminic acid binding lectin. Can inhibit fungal growth

Anti-Papillomavirus type 1E2-protein Antibody
STJ60006 100 µg
EUR 424
Description: Involved in the biosynthesis of rubber, an isoprenoid polymer (cis-1,4-polyisoprene), latex allergen

Anti-Papillomavirus type 1E2-protein Antibody
STJ60007 100 µg
EUR 424
Description: May be part of the rubber biosynthesis machinery. Plays a role in rubber elongation, Latex allergen

Anti-Papillomavirus type 1E2-protein Antibody
STJ60008 100 µg
EUR 424
Description: Involved in the biosynthesis of rubber, an isoprenoid polymer (cis-1,4-polyisoprene), latex allergen

Anti-Papillomavirus type 1E2-protein Antibody
STJ60009 100 µg
EUR 424
Description: Causes an allergic reaction in human. Major latex allergen, a major cause of anaphylaxis in susceptible individuals, especially health care workers. 92% of health care workers with latex allergy have IgE specific to the Hev b 5 protein

Anti-Papillomavirus type 1E2-protein Antibody
STJ60010 100 µg
EUR 424
Description: Causes an allergic reaction in human. Major latex allergen, a major cause of anaphylaxis in susceptible individuals, especially health care workers. 92% of health care workers with latex allergy have IgE specific to the Hev b 5 protein

Mouse antibody for Bovine Papillomavirus
5091 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Bovine Papillomavirus for WB, ELISA.

Mouse antibody for Bovine Papillomavirus
5095 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Bovine Papillomavirus for WB, ELISA.

Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280

Human papillomavirus PCR kit
PCR-H454-48D 50T
EUR 453

Human papillomavirus PCR kit
PCR-H454-96D 100T
EUR 572

Recombinant Human Papillomavirus 16
7-07774 100µg Ask for price

Recombinant Human Papillomavirus 16
7-07775 500µg Ask for price

Recombinant Human Papillomavirus 16
7-07776 1000µg Ask for price

Recombinant Human Papillomavirus 18
7-07777 100µg Ask for price

Recombinant Human Papillomavirus 18
7-07778 500µg Ask for price

Recombinant Human Papillomavirus 18
7-07779 1000µg Ask for price

Recombinant Human Papillomavirus 6
7-07780 100µg Ask for price

Recombinant Human Papillomavirus 6
7-07781 500µg Ask for price

Recombinant Human Papillomavirus 6
7-07782 1000µg Ask for price

Recombinant Human Papillomavirus 11
7-07783 100µg Ask for price

Recombinant Human Papillomavirus 11
7-07784 500µg Ask for price

Recombinant Human Papillomavirus 11
7-07785 1000µg Ask for price

Human papillomavirus ELISA Kit
ELA-E0787h 96 Tests
EUR 824

Human papillomavirus antibody(IgM) ELISA Kit
CSB-E08783h-24T 1 plate of 24 wells
EUR 165
Description: Quantitative sandwich ELISA kit for measuring Human papillomavirus antibody (IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human papillomavirus antibody(IgM) ELISA Kit
1-CSB-E08783h
  • EUR 602.00
  • EUR 4238.00
  • EUR 2256.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human papillomavirus antibody(IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Papillomavirus 16 Protein
20-abx260289
  • EUR 885.00
  • EUR 342.00
  • EUR 1609.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Papillomavirus 18 Protein
20-abx260290
  • EUR 885.00
  • EUR 342.00
  • EUR 1609.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Papillomavirus 6 Protein
20-abx260291
  • EUR 885.00
  • EUR 342.00
  • EUR 1609.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Papillomavirus 11 Protein
20-abx260292
  • EUR 885.00
  • EUR 342.00
  • EUR 1609.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Goat polyclonal antibody for Papillomavirus
5001 1 ml
EUR 316.44
Description: This is goat polyclonal antibody against Papillomavirus group for WB, ELISA.

Goat polyclonal antibody for Papillomavirus
6124 1 ml
EUR 321.88
Description: This is HRP conjugated goat polyclonal antibody against Papillomavirus group for WB, ELISA.

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC040502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC040502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC041058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC041058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC470502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC470502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC471058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC471058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCAP0502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCAP0502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCAP1058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCAP1058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCB0502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Biotin conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCB0502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Biotin conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC810502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC810502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC811058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC811058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC700502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC700502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC701058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC701058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC880502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC880502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC881058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC881058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC940502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF594 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC940502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF594 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC610502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC610502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC611058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC611058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC680502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF568 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC680502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF568 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC681058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF568 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC681058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF568 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCA0502-250 250uL
EUR 383
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), APC conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCA1058-250 250uL
EUR 383
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), APC conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNUM0502-50 50uL
EUR 395
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), 1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNUM1058-50 50uL
EUR 395
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), 1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCP0502-250 250uL
EUR 383
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), PerCP conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC050502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF405M conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC050502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF405M conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC051058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF405M conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC051058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF405M conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC400502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF640R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC400502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF640R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCP1058-250 250uL
EUR 383
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), PerCP conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCR0502-250 250uL
EUR 383
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), RPE conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCR1058-250 250uL
EUR 383
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), RPE conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNUB0502-100 100uL
EUR 209
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Concentration: 0.2mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNUB0502-500 500uL
EUR 458
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Concentration: 0.2mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNUB1058-100 100uL
EUR 209
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Concentration: 0.2mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNUB1058-500 500uL
EUR 458
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Concentration: 0.2mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC430502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF543 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC430502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF543 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC431058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF543 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC431058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF543 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCB1058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Biotin conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCB1058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Biotin conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCH0502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

First, the split-type ECL sensing platform can successfully keep away from interference from organic samples and adequately makes use of the ECL effectivity of the AuNC probe. Furthermore, the ultrahigh sensitivity assay of HPV DNA will be achieved with none complicated nucleic acid amplification method. Taking benefit of the above deserves of split-type detection, the ECL DNA sensor achieved ideally suited low detection of 6.eight aM and a large dynamic vary bridging 10 orders of magnitude HPV16 E7. Furthermore, along with its favorable and highly effective specificity, excessive sensitivity, and good selectivity, this technique might detect HPV16 E7 DNA in human samples, which confirmed nice consistency with the FDA-approved method (Hybrid seize 2, HC2).

Health Culture and Presenting a Paradigmatic Model Focusing on Human Papillomavirus Disease

Health Culture and Presenting a Paradigmatic Model Focusing on Human Papillomavirus Disease

Posted on by Brian Taylor

In this examine, we developed a paradigmatic mannequin focusing on human papillomavirus (HPV) ailments, to be able to formulate a idea by investigating pathology in well being tradition utilizing Grounded Theory, as an inductive and exploratory analysis technique. It was a qualitative examine, and knowledge had been collected utilizing in-depth interviews with 20 folks (10 males and 10 girls) with cultural and spiritual specialties (clergy). In whole, twenty interviews had been carried out (imply length = 45 min) utilizing a semi-structured information consisting of open-ended questions. All recordings had been transcribed verbatim in Persian.

All objects had been extracted based mostly on the contributors’ responses and associated literature. After knowledge assortment, the fundamental idea evaluation was carried out by way of the three steps as follows: free coding, axial encryption, the implementation, refinement, and writing the theories according to selective coding theoretical fashions. Finally, the paradigm mannequin was decided from the offered fashions. The paradigm mannequin emerged from professors, clergy, and approved folks, confirmed that spiritual taboos about sexually transmitted ailments; lack of clever administration, complete supervision, compliance with well being requirements within the nation, correct laws concerning sexually transmitted ailments as causal elements, consciousness, well being training within the nation

public demand for well being, particular person dignity, punishment for well being detractors, familiarity with particular person rights as intervening elements, concern for human lives, well being, and perception in fatalism; ethnic variations; irresponsibility; threat notion; excessive price of HPV vaccine; immorality in well being speech; disregard for folks’s lives; gender variations as contextual elements; and the results is rising burden of ailments because of sexually transmitted illness reminiscent of (HPV). It appears the general lack of a health-based method could possibly be a main concern because of the weak spot of cultural administration in society that requires the involvement and intervention of all policymakers, well being planners, approved folks, professors, elites, and clerics to regulate this main cultural well being downside.

Validation of the cobas 6800 human papillomavirus take a look at in major cervical screening

Evaluation of Human Papillomavirus (HPV) testing programs appropriate for large-scale organized cervical screening applications is required. We evaluated the cobas 6800 HPV take a look at system for detection of cervical intraepithelial neoplasia grade three or worse (CIN3+) when nested in an organized major HPV screening program, utilizing the cobas 4800 take a look at as comparator. The Karolinska University Hospital Cervical Cytology Biobank, containing frozen cervical samples from >700,000 girls collaborating in organized cervical screening, was linked to the Swedish nationwide cervical screening registry to determine 470 saved cervical samples taken <180 days earlier than histopathological analysis of CIN3+.

Two controls per case, with no irregular outcomes for two screening rounds, matched for age and sampling time had been additionally retrieved. Aliquots from 1406 girls had been retrieved and re-tested on the cobas 4800 system and examined on the cobas 6800 system. There was excessive reproducibility between the unique cobas 4800 HPV take a look at outcomes, and the cobas 4800 HPV re-testing carried out on the samples retrieved from biobank storage. 462/464 biobanked samples from girls with CIN3+ examined HPV-positive on the cobas 6800 system, akin to a relative sensitivity of 99.6%. 925/932 biobanked samples from management girls examined HPV-negative on the cobas 6800 platform, akin to a relative specificity of 99.2%.

By typical standards, the cobas 6800 was non-inferior each concerning relative sensitivity of >90% (non-inferiority p-value <0.0001) and relative specificity of >98% (non-inferiority p-value 0.006). We conclude that the cobas 6800 HPV take a look at system had related, excessive efficiency because the cobas 4800 such, when evaluated utilizing cervical samples taken earlier than CIN3+ in a real-life major HPV screening program.

Health Culture and Presenting a Paradigmatic Model Focusing on Human Papillomavirus Disease

Harnessing immunity for remedy in human papillomavirus pushed cancers

In persistent high-risk HPV an infection, viral gene expression can set off some necessary early adjustments to immune capabilities which act to guard the lesion from immune assault and subsequently promote its development and skill for sustained immune escape. This contains immune checkpoint-inhibitor ligand expression (e.g. PD-L1) by tumour or related immune cells that may block any anti-tumour T-cell effectors. While there are encouraging indicators of efficacy for most cancers immunotherapies together with with immune checkpoint inhibitors, therapeutic vaccines and adoptive cell therapies, general response and survival charges stay comparatively low.

HPV oncogene vaccination has proven some helpful efficacy in therapy of sufferers with high-grade lesions however was unable to regulate later stage cancers. To maximally exploit anti-tumour immune responses, the suppressive elements related to HPV carcinogenesis should be countered. Importantly, a mixture of chemotherapy, lowering immunosuppressive myeloid cells, with therapeutic HPV vaccination considerably improves affect on most cancers therapy. Many medical trials are investigating checkpoint inhibitor therapies in HPV related cancers however response charges are restricted; mixture with vaccination is being examined. Further investigation of how chemo- and/or radio-therapy can affect the restoration of efficient anti-tumour immunity is warranted. Understanding easy methods to optimally deploy and sequence typical and immunotherapies is the problem.

Human papillomavirus type 16 L1-capsids(HPV16L1) antibody (IgG) ELISA kit
1-CSB-EQ027477HU
  • EUR 602.00
  • EUR 4238.00
  • EUR 2256.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitative indirect ELISA kit for measuring Human papillomavirus type 16 L1-capsids(HPV16L1) antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit papillomavirus type 18 L1-capsids antibody(IgG)ELISA Kit
CSB-E14280Rb-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rabbit papillomavirus type 18 L1-capsids antibody (IgG) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rabbit papillomavirus type 18 L1-capsids antibody(IgG)ELISA Kit
1-CSB-E14280Rb
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit papillomavirus type 18 L1-capsids antibody(IgG) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

ELISA kit for Human papillomavirus type 16 L1-capsids (HPV16L1) antibody (IgG)
EK0269 96 tests
EUR 712
Description: Enzyme-linked immunosorbent assay kit for quantification of Human papillomavirus type 16 L1-capsids (HPV16L1) antibody (IgG) in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Rabbit Papillomavirus type 18 L1-capsids IgG antibody
KTE90138-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Rabbit Papillomavirus type 18 L1-capsids IgG antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rabbit Papillomavirus type 18 L1-capsids IgG antibody
KTE90138-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Rabbit Papillomavirus type 18 L1-capsids IgG antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rabbit Papillomavirus type 18 L1-capsids IgG antibody
KTE90138-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Rabbit Papillomavirus type 18 L1-capsids IgG antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human papillomavirus type 18 L1-capsids(HPV18L1) antibody (IgG) ELISA kit
CSB-EQ027476HU-24T 1 plate of 24 wells
EUR 165
Description: Qualitative indirect ELISA kit for measuring Human papillomavirus type 18 L1-capsids (HPV18L1) antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human papillomavirus type 18 L1-capsids(HPV18L1) antibody (IgG) ELISA kit
1-CSB-EQ027476HU
  • EUR 602.00
  • EUR 4238.00
  • EUR 2256.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitative indirect ELISA kit for measuring Human papillomavirus type 18 L1-capsids(HPV18L1) antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Papillomavirus L1-Capsids Antibody (IgG) (Human ) ELISA Kit (OKCA00473)
OKCA00473 96 Wells
EUR 859
Description: Description of target: Papillomavirus L1-Capsids Antibody (IgG);Species reactivity: Human ;Application: ;Assay info: Assay Methodology: Qualitative Reverse Capture ELISA;Sensitivity:

Human Papillomavirus Type 16 L1(HPV16L1）ELISA Kit
QY-E05547 96T
EUR 361

ELISA kit for Human papillomavirus type 18 L1-capsids (HPV18L1) antibody (IgG)
EK0271 96 tests
EUR 712
Description: Enzyme-linked immunosorbent assay kit for quantification of Human papillomavirus type 18 L1-capsids (HPV18L1) antibody (IgG) in samples from serum, plasma, tissue homogenates and other biological fluids.

Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) ELISA kit
CSB-EQ027478HU-24T 1 plate of 24 wells
EUR 165
Description: Qualitativeindirect ELISA kit for measuring Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) ELISA kit
1-CSB-EQ027478HU
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitativeindirect ELISA kit for measuring Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human papillomavirus type 18 L1 protein (L1)
1-CSB-RP083594v
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 18 L1 protein(L1),partial expressed in E.coli

Papillomavirus type 16 Protein E6 Antibody
20-abx110070
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Papillomavirus Type 18 L1 ?HPV18L1?ELISA Kit
201-12-2025 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Papillomavirus Type 18 L1(HPV18L1）ELISA Kit
QY-E01727 96T
EUR 394

Human Papillomavirus L1 (HPV L1) ELISA Kit
abx052655-96tests 96 tests
EUR 668

Human papillomavirus type 16(HPV16) antibody (IgM) ELISA kit
CSB-EQ027772HU-24T 1 plate of 24 wells
EUR 165
Description: Quantitative sandwich ELISA kit for measuring Human papillomavirus type 16 (HPV16) antibody (IgM) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human papillomavirus type 16(HPV16) antibody (IgM) ELISA kit
1-CSB-EQ027772HU
  • EUR 602.00
  • EUR 4238.00
  • EUR 2256.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human papillomavirus type 16(HPV16) antibody (IgM) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Papillomavirus type 16 Protein E6 Antibody (Biotin)
20-abx105746
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Papillomavirus type 16 Protein E6 Antibody (FITC)
20-abx107164
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Papillomavirus type 16 Protein E6 Antibody (HRP)
20-abx108584
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Papilloma Virus Type 16 L1 (HPV16 L1) ELISA Kit
abx050267-96tests 96 tests
EUR 668

Human Papilloma Virus Type 16 L1 (HPV 16 L1) Protein
abx060601-100ug 100 ug
EUR 1970

ELISA kit for Human papillomavirus type 16 (HPV16) antibody (IgG)
EK0268 96 tests
EUR 712
Description: Enzyme-linked immunosorbent assay kit for quantification of Human papillomavirus type 16 (HPV16) antibody (IgG) in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Human papillomavirus type 16 (HPV16) antibody (IgM)
EK0270 96 tests
EUR 712
Description: Enzyme-linked immunosorbent assay kit for quantification of Human papillomavirus type 16 (HPV16) antibody (IgM) in samples from serum, plasma, tissue homogenates and other biological fluids.

Human Papillomavirus Type 16-IgG (HPV16-IgG) ELISA Kit
abx051562-96tests 96 tests
EUR 668

ELISA kit for Human Papillomavirus L1 antibody (HPV-L1 Ab)
KTE62897-48T 48T
EUR 354
Description: Quantitative sandwich ELISA for measuring Human Papillomavirus L1 antibody (HPV-L1 Ab) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Papillomavirus L1 antibody (HPV-L1 Ab)
KTE62897-5platesof96wells 5 plates of 96 wells
EUR 2252
Description: Quantitative sandwich ELISA for measuring Human Papillomavirus L1 antibody (HPV-L1 Ab) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Papillomavirus L1 antibody (HPV-L1 Ab)
KTE62897-96T 96T
EUR 572
Description: Quantitative sandwich ELISA for measuring Human Papillomavirus L1 antibody (HPV-L1 Ab) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Chicken Papilloma Virus Type 16 L1 Antibody (HPV16 L1-Ab) ELISA Kit
abx050266-96tests 96 tests
EUR 692

Human Papilloma Virus Type 16 L1 Antibody (HPV16 L1-Ab) ELISA Kit
abx050289-96tests 96 tests
EUR 692

Papillomavirus 16 Protein
20-abx260289
  • EUR 885.00
  • EUR 342.00
  • EUR 1609.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Human papillomavirus type 16 Protein E6 (E6)
1-CSB-YP365854HML
  • EUR 430.00
  • EUR 234.00
  • EUR 1508.00
  • EUR 642.00
  • EUR 1009.00
  • EUR 291.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 16 Protein E6(E6) expressed in Yeast

Human papillomavirus type 16 Protein E7 (E7)
1-CSB-YP365855HML
  • EUR 430.00
  • EUR 234.00
  • EUR 1508.00
  • EUR 642.00
  • EUR 1009.00
  • EUR 291.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 16 Protein E7(E7) expressed in Yeast

Human papillomavirus type 16 Protein E6 (E6)
1-CSB-EP365854HML
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 16 Protein E6(E6) expressed in E.coli

Human papillomavirus type 16 Protein E7 (E7)
1-CSB-EP365855HML
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 16 Protein E7(E7) expressed in E.coli

Human papillomavirus type 16 Protein E7 (E7)
1-CSB-EP365855HMLe0
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 16 Protein E7(E7) expressed in E.coli

Human papillomavirus 16 PCR kit
PCR-H463-48D 50T
EUR 453

Human papillomavirus 16 PCR kit
PCR-H463-96D 100T
EUR 572

99445-16 DCT 16 X 100MM
99445-16 250/pk
EUR 96
Description: Disposable Culture Tubes; DCT's, CGW

Human papillomavirus type 16 Regulatory protein E2 (E2)
1-CSB-EP365852HML
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 16 Regulatory protein E2(E2) expressed in E.coli

Recombinant Human Papillomavirus 16
7-07774 100µg Ask for price

Recombinant Human Papillomavirus 16
7-07775 500µg Ask for price

Recombinant Human Papillomavirus 16
7-07776 1000µg Ask for price

HPV-16 L1 Antibody
abx021897-1mg 1 mg
EUR 599

HPV-16 L1 Antibody
abx021898-1mg 1 mg
EUR 599

Nucleo 9 Line 16 ELISA kit
55R-ORG711/16 16 Tests
EUR 399
Description: ELISA kit for the detection of Nucleo 9 Line 16 in the research laboratory

Human papillomavirus 16 RT PCR kit
RTq-H463-100D 100T
EUR 717

Human papillomavirus 16 RT PCR kit
RTq-H463-150D 150T
EUR 808

Human papillomavirus 16 RT PCR kit
RTq-H463-50D 50T
EUR 598

Human papillomavirus type 16 Minor capsid protein L2 (L2)
1-CSB-EP365848HML
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human papillomavirus type 16 Minor capsid protein L2(L2) expressed in E.coli

Mouse antibody for Human Papilloma virus L1 type 16
5301 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Human Papilloma virus L1 type 16 for WB, ELISA.

ANA 9 Line Immunoblot 16 ELISA kit
55R-ORG710/16 16 Tests
EUR 399
Description: ELISA kit for the detection of ANA 9 Line Immunoblot 16 in the research laboratory

Human papillomavirus 16 One-Step PCR kit
Oneq-H463-100D 100T
EUR 866

Human papillomavirus 16 One-Step PCR kit
Oneq-H463-150D 150T
EUR 981

Human papillomavirus 16 One-Step PCR kit
Oneq-H463-50D 50T
EUR 718

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC040502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC040502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC041058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC041058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF405S conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC470502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC470502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC471058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC471058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF647 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCAP0502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCAP0502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCAP1058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNCAP1058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCB0502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Biotin conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNCB0502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), Biotin conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC810502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC810502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC811058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC811058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF680R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC700502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC700502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC701058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC701058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF770 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC880502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC880502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC881058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC881058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF488A conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC940502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF594 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC940502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF594 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC610502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC610502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC611058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC611058-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF660R conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC680502-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF568 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(CAMVIR-1) Antibody
BNC680502-500 500uL
EUR 544
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(CAMVIR-1), CF568 conjugate, Concentration: 0.1mg/mL

Human Papillomavirus 16 (HPV16)(HPV16/1058) Antibody
BNC681058-100 100uL
EUR 199
Description: Primary antibody against Human Papillomavirus 16 (HPV16)(HPV16/1058), CF568 conjugate, Concentration: 0.1mg/mL

alignant transformation includes an orchestrated rearrangement of cell cycle regulation mechanisms that should steadiness autonomic mitogenic impulses and deleterious oncogenic stress. Human papillomavirus (HPV) an infection is very prevalent in populations across the globe, whereas the incidence of cervical most cancers is 0.15%. Since HPV an infection primes cervical keratinocytes to bear malignant transformation, we will assume that the steadiness between reworking mitogenic alerts and oncogenic stress isn’t attained.

Human papillomavirus infection status of single cells isolated from cervical cytology specimens by simple manual microdissection

Human papillomavirus infection status of single cells isolated from cervical cytology specimens by simple manual microdissection

Posted on by Brian Taylor

Human papillomavirus (HPV) testing with cytology triage for cervical most cancers screening has been confirmed to be helpful. It is taken into account {that a} important proportion of HPV-positive girls adopted by reflex cytology have had multiple-type HPV infections slightly than single-type infections. However, the results of multiple-type infections on adjustments within the cytomorphology of exfoliated cervical cells haven’t been investigated. The goal of this examine was to validate a simple manual microdissection (MMD) maneuver and examine the HPV infection status of single cells isolated from Papanicolaou (Pap) smear ready from girls with multiple-type infections.

Using cytology samples from 90 sufferers with irregular Pap smear outcomes, we evaluated the effectivity of the MMD process and decided the HPV infection status of single squamous intraepithelial lesion (SIL) cells microdissected from sufferers with multiple-type infection. In validating the MMD process, the HPV-positive price was 81.5% utilizing 119 MMD samples from the Pap smear in 61 instances with single-type infection. This MMD process was capable of effectively gather single cells. Of 119 MMD samples from 29 instances with multiple-type infection, the HPV-positive price was 42.9%, and most (96.1%) MMD samples exhibited just one genotype.

Our MMD maneuver efficiently recognized HPV genotypes utilizing single cells isolated from cytology specimens. A majority of single SIL cells ready from multiple-type infection instances turned out to comprise just one genotype. In the longer term, the MMD methodology may very well be utilized whereas learning the connection between the morphological adjustments exhibited by SIL cells on Pap smear and the contaminated HPV genotype. This article is protected by copyright. All rights reserved. The human papillomavirus (HPV) vaccine was launched into Thailand’s nationwide immunization program in 2017 for 11-12 yr old style women.

The goals of this examine had been to look at the epidemiological penalties and cost-effectiveness of a routine quadrivalent HPV (4vHPV) vaccination and the routine 4vHPV vaccination plus 5-year catch-up vaccination by evaluating with cervical most cancers screening solely (no vaccination) in Thailand. A transmission dynamic mannequin was used to evaluate the cost-effectiveness of the routine 4vHPV vaccination and the routine 4vHPV vaccination plus catch-up vaccination, in contrast with no vaccination (screening solely) in Thai inhabitants. The vaccination protection price assumptions had been 95% in 11-12-year-old women for the routine vaccination and 70% in 13-24 year-old females for the 5-year catch-up vaccination. Vaccination prices, direct medical prices of HPV-related ailments, and the quantity of high quality of life years (QALYs) gained had been calculated for over a 100-year time horizon with low cost price of 3%.

Single-administration, thermostable human papillomavirus vaccines ready with atomic layer deposition know-how

Cold-chain necessities have an effect on worldwide distribution of many vaccines. In addition, vaccines requiring a number of doses impose logistical and monetary burdens, in addition to affected person compliance boundaries. To tackle such limitations, we now have developed new applied sciences to organize thermostable, single-shot, prime-boost microparticle vaccines. Antigen/adjuvant formulations containing glass-forming polymers and trehalose first are spray-dried to kind glassy microparticles that confer thermostability. Atomic layer deposition (ALD) reactions performed in fluidized beds are then used to coat the microparticles with outlined numbers of molecular layers of alumina that modulate the timed launch of the internalized antigen and act as adjuvants.

We have used a mannequin HPV16 L1 capsomere antigen to guage the properties of these applied sciences. Thermostabilized powders containing HPV16 L1 capsomeres had been ready by spray-drying, coated by ALD with as much as 500 molecular layers of alumina, and injected into mice. Antigen distribution was assessed by live-animal IR dye monitoring of injected labeled antigen. Antibody responses had been measured weekly by ELISA, and neutralizing antibodies had been measured by pseudovirus neutralization assays at chosen time factors.

Thermostability was evaluated by measuring antibody responses after incubating ALD-coated antigen powders for one month at 50 °C. Single doses of the ALD-coated vaccine formulations elicited a prime-boost immune response, and produced neutralizing responses and antibody titers that had been equal or superior to traditional prime-boost doses of liquid formulations. Antibody titers had been unaffected by month-long incubation of the formulations at 50 °C. Single-dose, thermostable antigen preparations could overcome present limitations in HPV vaccine supply in addition to being extensively relevant to different antigens.

Human papillomavirus infection status of single cells isolated from cervical cytology specimens by simple manual microdissection

Peak neutralizing and cross-neutralizing antibody ranges to human papillomavirus sorts 6/16/18/31/33/45/52/58 induced by bivalent and quadrivalent HPV vaccines

We carried out an unbiased comparability of neutralizing and cross-neutralizing antibody (ab) ranges seven months after initiation of three-dose, six-month vaccination schedules with the bivalent and quadrivalent human papillomavirus (HPV) vaccines in adolescent Finnish and Indian females, respectively. We used a semi-automated Pseudovirion-Based Neutralization Assay and noticed considerably greater HPV16/18 peak ab-levels in bivalent as in comparison with quadrivalent vaccine recipients.

Bivalent vaccine induced cross-neutralizing HPV31/33/45/52/58 antibodies considerably extra often and to greater ranges than the quadrivalent vaccine. The correlation of bivalent vaccine-induced HPV45 ab-levels with HPV16/18 ab-levels was stronger than that of corresponding quadrivalent vaccine-induced ab-levels, suggesting a qualitatively totally different cross-reactive response. Our findings on the comparability of the immunogenicity of two HPV vaccine examined in two totally different populations point out that additional head-to-head research are warranted.

Human papillomavirus IgM(HPV-IgM)ELISA Kit
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  • 1 plate of 96 wells
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Adult Caucasian males with a medical and histological prognosis of PeIN, that’s, Bowenoid papulosis (BP), Bowen’s illness of penis (BDP) and erythroplasia of Queyrat (EQ) had been chosen and phenotyped from the medical data. DNA was extracted from blood and paraffin-embedded sections for HLA and HPV typing, respectively. Human leucocyte antigen allele frequencies had been in contrast with these derived from the UK-based Caucasian inhabitants.