Misinformation Drives Low Human Papillomavirus Vaccination Coverage in South African Girls Attending Private Schools

Cervical most cancers, brought on by persistent human papillomavirus (HPV) an infection, is the main reason behind feminine most cancers deaths in South Africa. In 2014, the South African National Department of Health launched a free public sector school-based HPV vaccination programme, concentrating on grade Four ladies aged ≥9 years. However, personal sector faculty ladies obtain HPV vaccination by way of their healthcare suppliers at value. This research investigated HPV vaccination information, attitudes and practices of caregivers of ladies aged ≥9 years in grades 4-7 attending South African personal faculties.

A hyperlink to a web based survey was circulated to caregivers by way of an electronic mail despatched to high school principals of all personal faculties in 4 provinces enrolling ladies in grades 4-7. Following a poor post-reminder response, a paid Facebook survey-linked advert concentrating on South African Facebook customers aged ≥25 years nationally was run for Four days, and positioned on the South African Vaccination and Immunisation Centre’s Facebook web page for 20 days. Of 615 respondents, 413 supplied HPV vaccination information and 455 accomplished the information and attitudes assessments. Most (76.5%) caregivers had good information and 45.3% had optimistic attitudes.

Of their daughters, 19.4% had obtained ≥1 dose of HPV vaccine. Of caregivers of unvaccinated ladies, 44.3% and 41.1%, respectively have been prepared to vaccinate their daughters if vaccination was supplied free and at their faculty. Caregivers of unvaccinated ladies have been extra seemingly [odds ratio (OR): 3.8] to have been influenced by “different” influences (primarily on-line articles and anecdotal vaccine harm reviews). Of caregivers influenced by their healthcare suppliers, caregivers of unvaccinated ladies have been extra seemingly (OR: 0.2) to be influenced by different medical practitioners.

Caregivers of vaccinated ladies have been extra more likely to have good information (OR: 3.6) and optimistic attitudes (OR: 5.2). Having good information strongly predicted (OR: 2.8) optimistic attitudes. Having unfavourable attitudes strongly predicted (OR: 0.2) ladies being unvaccinated. Providing free school-based HPV vaccination in the personal sector could not enhance HPV vaccination protection to an optimum degree. Since misinformation was the primary driver of unfavourable attitudes ensuing in <20% of ladies being vaccinated, an advocacy marketing campaign concentrating on all stakeholders is urgently wanted.

Persistent Human Papillomavirus Infection

Persistent an infection with oncogenic human papillomavirus (HPV) sorts is answerable for ~5% of human cancers. The HPV infectious cycle can maintain long-term an infection in stratified epithelia as a result of viral DNA is maintained as low copy quantity extrachromosomal plasmids in the dividing basal cells of a lesion, whereas progeny viral genomes are amplified to giant numbers in differentiated superficial cells. The viral E1 and E2 proteins provoke viral DNA replication and preserve and partition viral genomes, in live performance with the mobile replication equipment. Additionally, the E5, E6, and E7 proteins are required to evade host immune responses and to provide a mobile surroundings that helps viral DNA replication. An unlucky consequence of the manipulation of mobile proliferation and differentiation is that cells develop into at excessive threat for carcinogenesis.

The Human Papillomavirus (HPV) is the causative agent of various sorts of tumors, together with cervical cancers, non-melanoma pores and skin cancers, anogenital cancers, and head and neck cancers. Despite the vaccination campaigns applied over the past many years, we’re removed from eradicating HPV-driven malignancies. Moreover, the dearth of focused therapies to sort out HPV-related tumors exacerbates this downside. Biomarkers for early detection of the pathology and extra tailor-made therapeutic approaches are wanted, and an entire understanding of HPV-driven tumorigenesis is crucial to achieve this objective. In this evaluate, we overview the molecular pathways implicated in HPV an infection and carcinogenesis, emphasizing the potential targets for brand spanking new therapeutic methods in addition to new biomarkers.

Misinformation Drives Low Human Papillomavirus Vaccination Coverage in South African Girls Attending Private Schools

De-Escalated Adjuvant Therapy after Transoral Robotic Surgery for Human Papillomavirus-Related Oropharyngeal Carcinoma: The Sinai Robotic Surgery (SIRS) Trial

Treatment of human papillomavirus-related oropharyngeal squamous cell carcinoma (HPVOPC) outcomes in unprecedented excessive survival charges however probably pointless toxicity. We hypothesized that upfront surgical procedure and neck dissection adopted by reduced-dose adjuvant remedy for early and intermediate HPVOPC would finally consequence in equal progression-free survival (PFS) and total survival whereas decreasing toxicity. This research is a nonrandomized part II trial for early-stage HPVOPC handled with transoral robotic surgical procedure (TORS) adopted by reduced-dose radiotherapy.
Patients with beforehand untreated p16-positive HPVOPC and < 20 pack years’ smoking historical past have been enrolled. After robotic surgical procedure, sufferers have been assigned to group 1 (no poor threat options; surveillance), group 2 (intermediate pathologic threat components [perineural invasion, lymphovascular invasion]; 50-Gy radiotherapy), or group 3 (poor prognostic pathologic components [ECE, more than three positive lymph nodes and positive margin]; concurrent 56-Gy chemoradiotherapy with weekly cisplatin).
 Fifty-four sufferers have been evaluable; there have been 25 in group 1, 15 in group 2, and 14 in group 3. Median follow-up was 43.9 months (9.6-75.8). Disease-specific survival was 98.1%, and PFS was 90.7%. PFS likelihood by way of Kaplan-Meier was 91.3% for group 1, 86.7% for group 2, and 93.3% for group 3. There have been 4 locoregional failures (LRFs), together with one distant metastasis and one contralateral second major. Average time to LRF was 46.Three months (9.6-59.0); 4 LRFs have been efficiently salvaged, and the sufferers stay illness free (11.0-42.7 months); one topic stays alive with illness.

Human papillomavirus type 18(HPV18) antibody (IgG) Elisa Kit

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Human papillomavirus type 16 (HPV16) antibody (IgG) Elisa Kit

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ELISA kit for Human papillomavirus type 16 (HPV16) antibody (IgG)

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EUR 854.4
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ELISA kit for Human papillomavirus type 18 (HPV18)antibody (IgG)

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Description: Qualitative indirect ELISA kit for measuring Human papillomavirus type 18 L1-capsids(HPV18L1) antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

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Description: Qualitative indirect ELISA kit for measuring Human papillomavirus type 16 L1-capsids (HPV16L1) antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

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1-CSB-EQ027477HU
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Description: Rabbit (Oryctolagus cuniculus)

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EUR 680
Description: Rabbit (Oryctolagus cuniculus)

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Description: Rabbit (Oryctolagus cuniculus)

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EUR 680
Description: Rabbit (Oryctolagus cuniculus)

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Description: Quantitativesandwich ELISA kit for measuring Rabbit papillomavirus type 18 L1-capsids antibody (IgG) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

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Description: Quantitativesandwich ELISA kit for measuring Rabbit papillomavirus type 18 L1-capsids antibody(IgG) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

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EK714475 96 Wells
EUR 0.46

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EUR 789

Human papillomavirus type 16(HPV16) antibody (IgM) ELISA kit

CSB-EQ027772HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human papillomavirus type 16 (HPV16) antibody (IgM) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

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Description: Quantitative sandwich ELISA kit for measuring Human papillomavirus type 16(HPV16) antibody (IgM) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human papillomavirus type 18 (HPV18) antibody (IgM) ELISA kit

CSB-EQ028067HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human papillomavirus type 18 (HPV18) antibody (IgM) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human papillomavirus type 18 (HPV18) antibody (IgM) ELISA kit

1-CSB-EQ028067HU
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Description: Quantitativesandwich ELISA kit for measuring Human papillomavirus type 18 (HPV18) antibody (IgM) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

ELISA kit for Human papillomavirus antibody (IgG)

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EUR 854.4
Description: Enzyme-linked immunosorbent assay kit for quantification of Human papillomavirus antibody (IgG) in samples from serum, plasma, tissue homogenates and other biological fluids.

Human papillomavirus type 18 antibody (HPV18-Ab) ELISA Kit

SL3458Hu 96 Tests
EUR 468

Human papillomavirus type 16 antibody (HPV16-Ab) ELISA Kit

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EUR 468

Human Papillomavirus IgG antibody (HPV-Ab-IgG) ELISA Kit

AE62501HU-48Tests 48 Tests
EUR 360
Description: Human (Homo sapiens)

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AE62501HU-96Tests 96 Tests
EUR 680
Description: Human (Homo sapiens)

Human papillomavirus 6 antibody IgG (HPV6-IgG)ELISA Kit

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EUR 468

Human papillomavirus 18 antibody IgG (HPV18-IgG)ELISA Kit

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Human papillomavirus 11 antibody IgG (HPV11-IgG) ELISA Kit

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EUR 468

Human Papillomavirus Type 18 ?HPV18?ELISA Kit

201-12-2024 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Papillomavirus Type 18 (HPV18)ELISA Kit

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EUR 472.8

Human Papillomavirus Type 18(HPV18)ELISA Kit

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Human Papillomavirus IgG (HPV IgG) ELISA Kit

abx052750-96tests 96 tests
EUR 801.6

Human Papillomavirus IgG (HPV IgG) ELISA Kit

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human papillomavirus IgG,HPV-IgG ELISA Kit

201-12-1103 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human papillomavirus IgG(HPV-IgG) Elisa Kit

EK711272 96 Wells
EUR 0.16

Human papillomavirus IgG(HPV-IgG)ELISA Kit

GA-E1119HM-48T 48T
EUR 346.8

Human papillomavirus IgG(HPV-IgG)ELISA Kit

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EUR 559.2

Human papillomavirus IgG(HPV-IgG)ELISA Kit

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EUR 433.2

Human Papillomavirus Type 18 L1 ?HPV18L1?ELISA Kit

201-12-2025 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Papillomavirus Type 18 L1(HPV18L1)ELISA Kit

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EUR 472.8

Human Papillomavirus Type 16 L1(HPV16L1)ELISA Kit

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Human Papillomavirus Type 18 L1(HPV18L1)ELISA Kit

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Human Papillomavirus 6 IgG (HPV-6 IgG) ELISA Kit

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Human Papillomavirus 6 IgG (HPV-6 IgG) ELISA Kit

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Papillomavirus L1-Capsids Antibody (IgG) (Human ) ELISA Kit (OKCA00473)

OKCA00473 96 Wells
EUR 1030.8
Description: Description of target: Papillomavirus L1-Capsids Antibody (IgG);Species reactivity: Human ;Application: ;Assay info: Assay Methodology: Qualitative Reverse Capture ELISA;Sensitivity:

Human Papillomavirus 16 IgG (HPV-16 IgG) ELISA Kit

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Human Papillomavirus 16 IgG (HPV-16 IgG) ELISA Kit

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Human Papillomavirus 18 IgG (HPV-18 IgG) ELISA Kit

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EUR 493.75

Human papillomavirus 16 IgG (HPV16-IgG)ELISA Kit

SL1940Hu 96 Tests
EUR 468

Human papillomavirus antibody(IgM) Elisa Kit

EK714259 96 Wells
EUR 0.44

Human papillomavirus antibody(IgM) ELISA Kit

EK0267 96 tests
EUR 789

Human papillomavirus antibody(IgM) ELISA Kit

CSB-E08783h-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human papillomavirus antibody (IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human papillomavirus antibody(IgM) ELISA Kit

1-CSB-E08783h
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Papillomavirus type 16 Protein E6 Antibody

20-abx110070
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Papillomavirus type 18 Protein E7 Antibody

20-abx110071
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Papillomavirus type 16 Protein E6 Antibody

abx110070-100l 100 µl
EUR 162.5

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OKCA00473-96W - Papillomavirus L1-Capsids Antibody (IgG) (Human ) ELISA Kit

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EUR 700

Human papillomavirus type 6 L1-capsids(HPV6 L1) ELISA Kit

SL2625Hu 96 Tests
EUR 468

Human papillomavirus type 16 L1-capsids(HPV16 L1) ELISA Kit

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Human papillomavirus type 11 L1-capsids(HPV11 L1) ELISA Kit

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20-abx108584
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Papillomavirus type 18 Protein E7 Antibody (HRP)

20-abx108585
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Papillomavirus type 16 Protein E6 Antibody (HRP)

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EUR 362.5

Papillomavirus type 16 Protein E6 Antibody (HRP)

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EUR 162.5

Papillomavirus type 16 Protein E6 Antibody (HRP)

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EUR 250

Papillomavirus type 18 Protein E7 Antibody (HRP)

abx108585-100g 100 µg
EUR 362.5

Papillomavirus type 18 Protein E7 Antibody (HRP)

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EUR 162.5

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EUR 250

Human papillomavirus IgG,HPV-IgG ELISA Kit(Quantitative)

SL1330Hu_1 96 Tests Ask for price

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20-abx107164
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Papillomavirus type 18 Protein E7 Antibody (FITC)

20-abx107165
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Papillomavirus type 16 Protein E6 Antibody (FITC)

abx107164-100g 100 µg
EUR 362.5

Papillomavirus type 16 Protein E6 Antibody (FITC)

abx107164-20g 20 µg
EUR 162.5

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abx107164-50g 50 µg
EUR 250

Papillomavirus type 18 Protein E7 Antibody (FITC)

abx107165-100g 100 µg
EUR 362.5

Papillomavirus type 18 Protein E7 Antibody (FITC)

abx107165-20g 20 µg
EUR 162.5

Papillomavirus type 18 Protein E7 Antibody (FITC)

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EUR 250

Papillomavirus type 16 Protein E6 Antibody (Biotin)

20-abx105746
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Papillomavirus type 18 Protein E7 Antibody (Biotin)

20-abx105747
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Papillomavirus type 16 Protein E6 Antibody (Biotin)

abx105746-100g 100 µg
EUR 362.5

Papillomavirus type 16 Protein E6 Antibody (Biotin)

abx105746-20g 20 µg
EUR 162.5

Papillomavirus type 16 Protein E6 Antibody (Biotin)

abx105746-50g 50 µg
EUR 250

Papillomavirus type 18 Protein E7 Antibody (Biotin)

abx105747-100g 100 µg
EUR 362.5

Papillomavirus type 18 Protein E7 Antibody (Biotin)

abx105747-20g 20 µg
EUR 162.5

Papillomavirus type 18 Protein E7 Antibody (Biotin)

abx105747-50g 50 µg
EUR 250

Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) Elisa Kit

EK714431 96 Wells
EUR 0.45

Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) ELISA kit

CSB-EQ027478HU-24T 1 plate of 24 wells
EUR 198
Description: Qualitativeindirect ELISA kit for measuring Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) ELISA kit

1-CSB-EQ027478HU
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  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Qualitativeindirect ELISA kit for measuring Human high risk papillomavirus L1-capsids (HR-HPVL1) antibody (IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human papillomavirus ELISA Kit

ELA-E0787h 96 Tests
EUR 988.8

Human Papillomavirus Type 16 Major Capsid Protein L1 (HPV16 L1) Antibody

abx201362-100l 100 µl
EUR 450

Human Papillomavirus Type 16 Major Capsid Protein L1 (HPV16 L1) Antibody

abx201362-50l 50 µl
EUR 312.5

Human papillomavirus type 18 Protein E7 (E7)

1-CSB-YP361948HMN
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  • 100ug
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  • 1MG
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  • 50ug
Description: Recombinant Human papillomavirus type 18 Protein E7(E7) expressed in Yeast

Human papillomavirus type 16 Protein E6 (E6)

1-CSB-YP365854HML
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  • 100ug
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Description: Recombinant Human papillomavirus type 16 Protein E6(E6) expressed in Yeast

Human papillomavirus type 16 Protein E7 (E7)

1-CSB-YP365855HML
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  • 100ug
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Description: Recombinant Human papillomavirus type 16 Protein E7(E7) expressed in Yeast

Human papillomavirus type 18 L1 protein (L1)

1-CSB-RP083594v
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  • 100ug
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Description: Recombinant Human papillomavirus type 18 L1 protein(L1),partial expressed in E.coli

Human papillomavirus type 18 Protein E7 (E7)

1-CSB-EP361948HMN
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  • 100ug
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Description: Recombinant Human papillomavirus type 18 Protein E7(E7) expressed in E.coli

Human papillomavirus type 16 Protein E6 (E6)

1-CSB-EP365854HML
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  • 100ug
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  • 1MG
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  • 50ug
Description: Recombinant Human papillomavirus type 16 Protein E6(E6) expressed in E.coli

Human papillomavirus type 16 Protein E7 (E7)

1-CSB-EP365855HML
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  • 100ug
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Description: Recombinant Human papillomavirus type 16 Protein E7(E7) expressed in E.coli

Human papillomavirus type 16 Protein E7 (E7)

1-CSB-EP365855HMLe0
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  • 100ug
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Description: Recombinant Human papillomavirus type 16 Protein E7(E7) expressed in E.coli

Human papillomavirus type 52 Protein E6 (E6)

1-CSB-EP334186HNY
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  • 100ug
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  • 1MG
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Description: Recombinant Human papillomavirus type 52 Protein E6(E6) expressed in E.coli

Human papillomavirus type 52 Protein E7 (E7)

1-CSB-EP339740HNY
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  • 100ug
  • 10ug
  • 1MG
  • 200ug
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  • 50ug
Description: Recombinant Human papillomavirus type 52 Protein E7(E7) expressed in E.coli

ELISA kit for Human Papillomavirus L1 antibody (HPV-L1 Ab)

KTE62897-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Human Papillomavirus L1 antibody (HPV-L1 Ab) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Papillomavirus L1 antibody (HPV-L1 Ab)

KTE62897-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Human Papillomavirus L1 antibody (HPV-L1 Ab) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Papillomavirus L1 antibody (HPV-L1 Ab)

KTE62897-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Human Papillomavirus L1 antibody (HPV-L1 Ab) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human Papillomavirus IgM antibody (HPV-Ab-IgM) ELISA Kit

AE62502HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human Papillomavirus IgM antibody (HPV-Ab-IgM) ELISA Kit

AE62502HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human Papillomavirus(PV) ELISA Kit

NSL1186Hu 96 wells
EUR 468

Human papillomavirus,HPV ELISA Kit

201-12-1101 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
The outcomes point out that upfront surgical procedure with neck dissection with reduced-dose radiation for T1-2, N1 stage (by the eighth version American Joint Committee on Cancer staging guide) HPVOPC outcomes in favorable survival with glorious operate in this inhabitants. These outcomes assist radiation dose discount after TORS as a de-escalation technique in HPVOPC.